antibacterial, antifungal, and cytotoxic evaluation of some quinazolinone derivatives
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منابع مشابه
antibacterial, antifungal and cytotoxic evaluation of some new quinazolinone derivatives
quinazolinone ring system is renown because of its wide spectrum of pharmacological activities due to various substitutions on this ring system. in this study, the minimum inhibitory concentration of the synthesized compounds in our laboratory was determined by micro dilution alamar blue ® assay against six strains of bacteria (three gram-positive and three gram-negative) and three strains of f...
متن کاملAntibacterial, antifungal and cytotoxic evaluation of some new 2,3-disubstituted 4(3H)-quinazolinone derivatives
In this study antibacterial, antifungal and cytotoxic effects of some new 2,3-disubstituted 4(3H)-quinazolinone derivatives have been evaluated. The in vitro antibacterial and antifungal tests of new synthesized compounds were performed using MABA method against six strains of bacteria (three Grampositive and three Gram-negative) and three strains of fungi. Also Minimum Bactericidal Concentrati...
متن کاملsynthesis and antibacterial, antifungal and cytotoxic evaluation of some new 2,3-disubstituted 4(3h)-quinazolinone derivatives
متن کامل
antibacterial, antifungal and cytotoxic evaluation of some new 2,3-disubstituted 4(3h)-quinazolinone derivatives
in this study antibacterial, antifungal and cytotoxic effects of some new 2,3-disubstituted 4(3h)-quinazolinone derivatives have been evaluated. the in vitro antibacterial and antifungal tests of new synthesized compounds were performed using maba method against six strains of bacteria (three gram-positive and three gram-negative) and three strains of fungi. also minimum bactericidal concentrat...
متن کاملBiological Evaluation of Heterocycle Moiety of Some Novel azoles Derivatives as Antibacterial and Antifungal potential Agents
Background & Objective: Azole nucleuses are very important part of antimicrobial, analgesic and anti-inflammatory drugs. The azole class of compounds is the most popular among the antibacterial and antifungal classes because of its lower toxicity, higher efficacy and a broad spectrum of activity. Today, Efforts have focused on the development of new, less toxic and more efficacious antifungal a...
متن کاملSynthesis of Azole-containing Piperazine Derivatives and Evaluation of their Antibacterial, Antifungal and Cytotoxic Activities
A series of azole-containing piperazine derivatives have been designed and synthesized. The obtained compounds were investigated in vitro for their antibacterial, antifungal and cytotoxic activities. The preliminary results showed that most compounds exhibited moderate to significant antibacterial and antifungal activities in vitro. 1-(4-((4-chlorophenyl) (phenyl)methyl)piperazin-1-yl)-2-(1H-im...
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عنوان ژورنال:
research in pharmaceutical sciencesجلد ۷، شماره ۵، صفحات ۰-۰
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